Imaging tumor sensitivity to a bioreductive prodrug: two for the price of one!
نویسنده
چکیده
Hypoxia is an important characteristic of many solid tumors and has a major negative effect on treatment response. A way to combat this effect is with drugs called "bioreductive prodrugs" or "hypoxic cytotoxins," which are metabolized under hypoxia to toxic species. However, the patients with hypoxic tumors need to be identified.
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عنوان ژورنال:
- Clinical cancer research : an official journal of the American Association for Cancer Research
دوره 18 6 شماره
صفحات -
تاریخ انتشار 2012